Apple has defined some best practices to be taken when using Profiles. Obviously these don’t cover every situation, but they cover all but edge cases and lay out a pretty good description of why you should do the things we’ve mostly figured out to do by trial and error thus far. Great job to the OS X Server documentation team! https://help.apple.com/profilemanager/mac/5.1.5/#/apdE3493-C50A-4E9E-A1B6-CBCBC8C73507